Hydrogen Rich Water

Hydrogen Rich Water 24392

"This review and others have documented the clinical use of hydrogen is very promising for treating many acute and chronic illnesses and conditions, in addition to its usefulness in support of the maintenance of good health. What began in Japan and the Far East as preliminary results on the clinical use of hydrogen has continued there and elsewhere, to the point where there are now a vital number of scientific and clinical studies that encourage the use of hydrogen as a primary or supportive part of clinical care.

With its potent and distinctive antioxidant properties, gene regulatory abilities, and rapid rates of diffusion across tissue and cellular barriers, as well as its excellent safety record, hydrogen has many unique characteristics that make it very beneficial for use in medicine and health. Its systemic properties and exceptional penetration ab- ilities allow hydrogen to be effective under conditions of poor blood circulation and other circumstances that limit many other types of systemic treatments.

The clinical justification for hydrogen use is growing because:

1) Redox imbalance and the extra production of ROS and RNS (increasing oxidative stress) have been implicated in several, if not all, pathophysiological mechanisms resulting in a huge array of medical conditions and diseases. Hydrogen is beneficial because of its powerful free-radical scavenging properties that greatly reduce strong mobile oxidants, but it does not affect important signaling pathways that depend on mild cellular oxi- dants.

2) Hydrogen is effective in reducing signs and symptoms and improving quality of life in a huge array of clinical conditions. Because most of its consequences are often indirect, such as reducing excess oxidative stress, hy- drogen is beneficial for many apparently unrelated clinical conditions that are linked to redox imbalances. Often these conditions don"t have definitive treatments that eliminate the illness. In such circumstances, hydrogen may be used in conjunction with less than effective therapies to improve clinical outcomes.

3) Perhaps its most useful property is that hydrogen does not interfere with the underlying mechanisms of most clinical treatments. Thus, its actual value could be in adjuvant treatment, along with standard treatments for many clinical problems.

4) An important factor is that the safety of hydrogen and that no negative effects of hydrogen have been described. This is also very important, since many drugs are limited in their use due to toxicity, adverse reactions, and unfavorable dose-response characteristics. Hydrogen does not have these issues.

5) The simplicity of hydrogen administration is a useful characteristic. This is where H2-enriched water has an ad- vantage over other methods of hydrogen delivery. Drinking H2-enriched water can be performed on a long-term basis without any special requirements for administration.

Basic and clinical study on the use of hydrogen for acute and chronic illnesses will continue to improve our comprehension of the mechanism of action of hydrogen treatment.

1) Hydrogen can promote changes in the expression and levels of particular proteins by regulating gene expression. Of particular importance is that hydrogen can inhibit or change the expression patterns of pro- inflammatory, pro-allergic, pro-apoptotic and pro-oxidative proteins. Many, if not most, of these proteins are over-expressed in many different chronic and acute ailments. How hydrogen affects the expression of particular proteins remains an important question that"s currently a subject of research in several laboratories.

2) The cellular receptors for hydrogen and the mechanisms of hydrogen activity in the level of cellular mem- branes, enzymes, protein synthesis, and gene regulation might have to be investigated. Little is actually known about these molecular interactions involving hydrogen inside cells and cells. This will have to also be investi- gated in simple in vitro models so as to eventually understand more complex in vivo environments.

3) Hydrogen can swiftly penetrate into tissues and cells. Further investigation is needed to track the actual levels of hydrogen in the microcirculation and target cells, especially when hydrogen is administered for long periods of time. We don"t yet know the levels of hydrogen administration which offer steady state and effective concentrations of hydrogen in a variety of tissues and cells.

4) The clinical uses of hydrogen has to be further investigated. This salient worth reading link has a few thought-provoking suggestions for the inner workings of this view. Should people want to dig up further on per your request, there are many resources you could investigate. The majority of the published research on hydrogen has used animal models. Although this has been extremely useful, it is now time to change the focus of study to patients with acute and chronic clinical problems.

5) There are a few advantages and disadvantages in the various ways hydrogen is administered, and this should be further researched. Although inhalation of H2 gas has an advantage since it"s simple to administer; it also has some disadvantages, such as reproducibility of delivering the identical dose of H2 in different patients be- cause of variations in the amounts that effectively reach the microcirculation and cells. In addition, it requires high- pressure containers and pressure regulators to deliver the required amounts of hydrogen gas, and the individual must use a mask or nasal insert. On the other hand, H2-enriched water could be readily and accurately delivered without any special apparatus. With any delivery method there"s the issue of understanding the effective levels of hydrogen which reach the target tissues, and this will remain an important research issue.

6) The increased use of controlled, randomized clinical trials will improve our understanding of the advantages of hydrogen for various acute and chronic conditions. Until recently few clinical trials have used rigorous criteria for analysis of clinical consequences. Tour Vitamink contains more concerning how to ponder this activity. Many trials have been open label in design, which is expected for initial clin- ical investigations. In the future it"s expected that more carefully designed (and more expensive!) Placebo-controlled, blinded, randomized clinical trials will be required to confirm the clinical benefits of hydrogen. Finally, the use of hydrogen for acute and chronic medical conditions is rapidly being eclipsed by the use of hydrogen for health maintenance, exercise and physical performance, in addition to aging. These areas of hydrogen usage will continue to grow and will ultimately dwarf the current clinical uses of hydrogen in our society".

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